Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data

Genetic variation modulates gene expression transcriptionally or post-transcriptionally, and can profoundly alter an individual’s phenotype. Measuring allelic differential expression at heterozygous loci within an individual, a phenomenon called allele-specific expression (ASE), can assist in identi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wood, David L. A., Nones, Katia, Steptoe, Anita, Christ, Angelika, Harliwong, Ivon, Newell, Felicity, Bruxner, Timothy J. C., Miller, David, Cloonan, Nicole, Grimmond, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428808/
https://ncbi.nlm.nih.gov/pubmed/25965996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126911
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