The Structure of an NDR/LATS Kinase–Mob Complex Reveals a Novel Kinase–Coactivator System and Substrate Docking Mechanism

Eukaryotic cells commonly use protein kinases in signaling systems that relay information and control a wide range of processes. These enzymes have a fundamentally similar structure, but achieve functional diversity through variable regions that determine how the catalytic core is activated and recr...

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Udgivet i:PLoS Biol
Main Authors: Gógl, Gergő, Schneider, Kyle D., Yeh, Brian J., Alam, Nashida, Nguyen Ba, Alex N., Moses, Alan M., Hetényi, Csaba, Reményi, Attila, Weiss, Eric L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428629/
https://ncbi.nlm.nih.gov/pubmed/25966461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002146
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