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CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
Polycomb and trithorax group proteins encode the epigenetic memory of cellular positional identity by establishing inheritable domains of repressive and active chromatin within the Hox clusters. Here, we demonstrate that the CCCTC-binding factor (CTCF) functions to insulate these adjacent yet antago...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428148/ https://ncbi.nlm.nih.gov/pubmed/25722416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1262088 |
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