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Trichostatin A Rescues the Disrupted Imprinting Induced by Somatic Cell Nuclear Transfer in Pigs

Imprinting disorders induced by somatic cell nuclear transfer (SCNT) usually lead to the abnormalities of cloned animals and low cloning efficiency. Histone deacetylase inhibitors have been shown to improve gene expression, genomic methylation reprogramming and the development of cloned embryos, how...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huan, Yanjun, Zhu, Jiang, Huang, Bo, Mu, Yanshuang, Kong, Qingran, Liu, Zhonghua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427324/
https://ncbi.nlm.nih.gov/pubmed/25962071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126607
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