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Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear Transfer

The low success rate of somatic cell nuclear transfer (SCNT) in mammalian cloning is largely due to imprinting problems. However, little is known about the mechanisms of reprogramming imprinted genes during SCNT. Parental origin-specific DNA methylation regulates the monoallelic expression of imprin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wei, Yanchang, Huan, Yanjun, Shi, Yongqian, Liu, Zhongfeng, Bou, Gerelchimeg, Luo, Yibo, Zhang, Li, Yang, Cairong, Kong, Qingran, Tian, Jiangtian, Xia, Ping, Sun, Qing-Yuan, Liu, ZhongHua
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098883/
https://ncbi.nlm.nih.gov/pubmed/21625467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020154
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