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Trichostatin A Rescues the Disrupted Imprinting Induced by Somatic Cell Nuclear Transfer in Pigs

Imprinting disorders induced by somatic cell nuclear transfer (SCNT) usually lead to the abnormalities of cloned animals and low cloning efficiency. Histone deacetylase inhibitors have been shown to improve gene expression, genomic methylation reprogramming and the development of cloned embryos, how...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Huan, Yanjun, Zhu, Jiang, Huang, Bo, Mu, Yanshuang, Kong, Qingran, Liu, Zhonghua
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427324/
https://ncbi.nlm.nih.gov/pubmed/25962071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126607
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