The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor

Defining the molecular networks that drive breast cancer has led to therapeutic interventions and improved patient survival. However, the aggressive triple-negative breast cancer subtype (TNBC) remains recalcitrant to targeted therapies because its molecular etiology is poorly defined. In this study...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Karlin, Kristen L., Mondal, Gourish, Hartman, Jessica K., Tyagi, Siddhartha, Kurley, Sarah J., Bland, Chris S., Hsu, Tiffany Y.T., Renwick, Alexander, Fang, Justin E., Migliaccio, Ilenia, Callaway, Celetta, Nair, Amritha, Dominguez-Vidana, Rocio, Nguyen, Don X., Osborne, C. Kent, Schiff, Rachel, Yu-Lee, Li-Yuan, Jung, Sung Y., Edwards, Dean P., Hilsenbeck, Susan G., Rosen, Jeffrey M., Zhang, Xiang, Shaw, Chad A., Couch, Fergus J., Westbrook, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427000/
https://ncbi.nlm.nih.gov/pubmed/25453754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.011
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