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BRCA2 localization to the midbody by Filamin A regulates CEP55 signaling and completion of cytokinesis
Disruption of the BRCA2 tumor suppressor is associated with structural and numerical chromosomal defects. The numerical abnormalities in BRCA2 deficient cells may partly result from aberrations in cell division caused by disruption of BRCA2 during cytokinesis. Here we show that BRCA2 is a component...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419138/ https://ncbi.nlm.nih.gov/pubmed/22771033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.008 |
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