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Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55

The ESCRT (Endosomal Sorting Complex Required for Transport) machinery is required for the scission of membrane necks in processes including the budding of HIV-1, and cytokinesis. An essential step in cytokinesis is recruitment of the ESCRT-I complex and the ESCRT associated protein ALIX to the midb...

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Autores principales: Lee, Hyung Ho, Elia, Natalie, Ghirlando, Rodolfo, Lippincott-Schwartz, Jennifer, Hurley, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720046/
https://ncbi.nlm.nih.gov/pubmed/18948538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162042
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