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Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
Activation-induced cytidine deaminase (AID) is essential for antibody class switch recombination (CSR) and somatic hypermutation (SHM). AID originally was postulated to function as an RNA-editing enzyme, based on its strong homology with apolipoprotein B mRNA-editing enzyme, catalytic polypeptide 1...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426456/ https://ncbi.nlm.nih.gov/pubmed/25902538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506167112 |
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