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Structural Conversion of Aβ(17–42) Peptides from Disordered Oligomers to U-Shape Protofilaments via Multiple Kinetic Pathways
Discovering the mechanisms by which proteins aggregate into fibrils is an essential first step in understanding the molecular level processes underlying neurodegenerative diseases such as Alzheimer’s and Parkinson's. The goal of this work is to provide insights into the structural changes that...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4425657/ https://ncbi.nlm.nih.gov/pubmed/25955249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004258 |
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