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Spontaneous Formation of Twisted Aβ(16-22) Fibrils in Large-Scale Molecular-Dynamics Simulations
Protein aggregation is associated with fatal neurodegenerative diseases, including Alzheimer's and Parkinson's. Mapping out kinetics along the aggregation pathway could provide valuable insights into the mechanisms that drive oligomerization and fibrillization, but that is beyond the curre...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218340/ https://ncbi.nlm.nih.gov/pubmed/22098748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.042 |
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