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Spontaneous Formation of Twisted Aβ(16-22) Fibrils in Large-Scale Molecular-Dynamics Simulations
Protein aggregation is associated with fatal neurodegenerative diseases, including Alzheimer's and Parkinson's. Mapping out kinetics along the aggregation pathway could provide valuable insights into the mechanisms that drive oligomerization and fibrillization, but that is beyond the curre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218340/ https://ncbi.nlm.nih.gov/pubmed/22098748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.042 |
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