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COMPUTER SIMULATION STUDY OF AMYLOID FIBRIL FORMATION BY PALINDROMIC SEQUENCES IN PRION PEPTIDES

We simulate the aggregation of large systems containing palindromic peptides from the Syrian hamster prion protein SHaPrP 113–120 (AGAAAAGA) and the mouse prion protein MoPrP 111–120 (VAGAAAAGAV) and eight sequence variations: GAAAAAAG, (AG)(4), A8, GAAAGAAA, A10, V10, GAVAAAAVAG, and VAVAAAAVAV The...

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Detalhes bibliográficos
Main Authors: Wagoner, Victoria, Cheon, Mookyung, Chang, Iksoo, Hall, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448282/
https://ncbi.nlm.nih.gov/pubmed/21557317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23034
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