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COMPUTER SIMULATION STUDY OF AMYLOID FIBRIL FORMATION BY PALINDROMIC SEQUENCES IN PRION PEPTIDES

We simulate the aggregation of large systems containing palindromic peptides from the Syrian hamster prion protein SHaPrP 113–120 (AGAAAAGA) and the mouse prion protein MoPrP 111–120 (VAGAAAAGAV) and eight sequence variations: GAAAAAAG, (AG)(4), A8, GAAAGAAA, A10, V10, GAVAAAAVAG, and VAVAAAAVAV The...

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Bibliografiske detaljer
Main Authors: Wagoner, Victoria, Cheon, Mookyung, Chang, Iksoo, Hall, Carol
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448282/
https://ncbi.nlm.nih.gov/pubmed/21557317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23034
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