Tris (dibenzylideneacetone) dipalladium (Tris DBA), an N-myristoyltransferase 1 inhibitor, is effective against melanoma growth in vitro and in vivo

PURPOSE: Melanoma is a solid tumor that is notoriously resistant to chemotherapy, and its incidence is rapidly increasing. Recently, several signaling pathways have been demonstrated to contribute to melanoma tumorigenesis, including constitutive activation of MAP kinase, Akt and Stat-3. The activat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Bhandarkar, Sulochana S., Bromberg, Jacqueline, Carrillo, Carol, Selvakumar, Ponniah, Sharma, Rajendra K, Perry, Betsy N, Govindarajan, Baskaran, Fried, Levi, Sohn, Allie, Reddy, Kalpana, Arbiser, Jack L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423743/
https://ncbi.nlm.nih.gov/pubmed/18794083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0405
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge