Tris (dibenzylideneacetone) dipalladium (Tris DBA), an N-myristoyltransferase 1 inhibitor, is effective against melanoma growth in vitro and in vivo

PURPOSE: Melanoma is a solid tumor that is notoriously resistant to chemotherapy, and its incidence is rapidly increasing. Recently, several signaling pathways have been demonstrated to contribute to melanoma tumorigenesis, including constitutive activation of MAP kinase, Akt and Stat-3. The activat...

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Publicat a:Clin Cancer Res
Autors principals: Bhandarkar, Sulochana S., Bromberg, Jacqueline, Carrillo, Carol, Selvakumar, Ponniah, Sharma, Rajendra K, Perry, Betsy N, Govindarajan, Baskaran, Fried, Levi, Sohn, Allie, Reddy, Kalpana, Arbiser, Jack L
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423743/
https://ncbi.nlm.nih.gov/pubmed/18794083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0405
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