Tris (dibenzylideneacetone) dipalladium (Tris DBA), an N-myristoyltransferase 1 inhibitor, is effective against melanoma growth in vitro and in vivo

PURPOSE: Melanoma is a solid tumor that is notoriously resistant to chemotherapy, and its incidence is rapidly increasing. Recently, several signaling pathways have been demonstrated to contribute to melanoma tumorigenesis, including constitutive activation of MAP kinase, Akt and Stat-3. The activat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Cancer Res
Prif Awduron: Bhandarkar, Sulochana S., Bromberg, Jacqueline, Carrillo, Carol, Selvakumar, Ponniah, Sharma, Rajendra K, Perry, Betsy N, Govindarajan, Baskaran, Fried, Levi, Sohn, Allie, Reddy, Kalpana, Arbiser, Jack L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423743/
https://ncbi.nlm.nih.gov/pubmed/18794083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0405
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