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Role of RNase H1 in DNA repair: removal of single ribonucleotide misincorporated into DNA in collaboration with RNase H2

Several RNases H1 cleave the RNA-DNA junction of Okazaki fragment-like RNA-DNA/DNA substrate. This activity, termed 3’-junction ribonuclease (3’-JRNase) activity, is different from the 5’-JRNase activity of RNase H2 that cleaves the 5’-side of the ribonucleotide of the RNA-DNA junction and is requir...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Tannous, Elias, Kanaya, Eiko, Kanaya, Shigenori
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423430/
https://ncbi.nlm.nih.gov/pubmed/25951507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09969
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