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RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
The chemical identity and integrity of the genome is challenged by the incorporation of ribonucleoside triphosphates (rNTPs) in place of deoxyribonucleoside triphosphates (dNTPs) during replication. Misincorporation is limited by the selectivity of DNA replicases. We show that accumulation of ribonu...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262129/ https://ncbi.nlm.nih.gov/pubmed/22244334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.019 |
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