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RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA

The chemical identity and integrity of the genome is challenged by the incorporation of ribonucleoside triphosphates (rNTPs) in place of deoxyribonucleoside triphosphates (dNTPs) during replication. Misincorporation is limited by the selectivity of DNA replicases. We show that accumulation of ribonu...

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Detaylı Bibliyografya
Asıl Yazarlar: Lazzaro, Federico, Novarina, Daniele, Amara, Flavio, Watt, Danielle L., Stone, Jana E., Costanzo, Vincenzo, Burgers, Peter M., Kunkel, Thomas A., Plevani, Paolo, Muzi-Falconi, Marco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262129/
https://ncbi.nlm.nih.gov/pubmed/22244334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.019
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