c-Abl antagonizes the YAP oncogenic function

YES-associated protein (YAP) is a central transcription coactivator that functions as an oncogene in a number of experimental systems. However, under DNA damage, YAP activates pro-apoptotic genes in conjunction with p73. This program switching is mediated by c-Abl (Abelson murine leukemia viral onco...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Keshet, R, Adler, J, Ricardo Lax, I, Shanzer, M, Porat, Z, Reuven, N, Shaul, Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423178/
https://ncbi.nlm.nih.gov/pubmed/25361080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.182
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