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c-Abl downregulates the slow phase of double-strand break repair

c-Abl tyrosine kinase is activated by agents that induce double-strand DNA breaks (DSBs) and interacts with key components of the DNA damage response and of the DSB repair machinery. However, the functional significance of c-Abl in these processes, remained unclear. In this study, we demonstrate, us...

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Detalhes bibliográficos
Main Authors: Meltser, V, Ben-Yehoyada, M, Reuven, N, Shaul, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032510/
https://ncbi.nlm.nih.gov/pubmed/21364621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2009.21
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