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c-Abl antagonizes the YAP oncogenic function
YES-associated protein (YAP) is a central transcription coactivator that functions as an oncogene in a number of experimental systems. However, under DNA damage, YAP activates pro-apoptotic genes in conjunction with p73. This program switching is mediated by c-Abl (Abelson murine leukemia viral onco...
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| Pubblicato in: | Cell Death Differ |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423178/ https://ncbi.nlm.nih.gov/pubmed/25361080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.182 |
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