Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin. Role of platelet activation, fibrinogen, and two distinct membrane receptors.

Three preparations of purified von Willebrand factor (vWF), obtained from unrelated patients affected by type IIB von Willebrand disease, were found to have normal sialic acid content (between 129 and 170 nmol/mg of vWF, as compared with 158 +/- 17 nmol/mg in four normal preparations) and to induce...

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Detalhes bibliográficos
Main Authors: De Marco, L, Mazzuccato, M, Grazia Del Ben, M, Budde, U, Federici, A B, Girolami, A, Ruggeri, Z M
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC442260/
https://ncbi.nlm.nih.gov/pubmed/3038958
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