miR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes

miR-122 is an abundant, liver-specific microRNA that is required for efficient amplification of hepatitis C virus (HCV) RNA. Recent studies with a miR-122-specific locked nucleic acid antagomir have shown it to be an important host target for therapeutic intervention. However, considerable controver...

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Detaylı Bibliyografya
Yayımlandı:Antiviral Res
Asıl Yazarlar: Villanueva, Rodrigo A., Jangra, Rohit K., Yi, MinKyung, Pyles, Rick, Bourne, Nigel, Lemon, Stanley M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422393/
https://ncbi.nlm.nih.gov/pubmed/20637242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.07.004
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