Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein

Helicobacter pylori cagA-positive strain delivers the CagA oncoprotein into gastric epithelial cells and at the same time elicits stomach inflammation. To experimentally investigate the pathophysiological interplay between CagA and inflammation, transgenic mice systemically expressing the bacterial...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Suzuki, Nobumi, Murata-Kamiya, Naoko, Yanagiya, Kohei, Suda, Wataru, Hattori, Masahira, Kanda, Hiroaki, Bingo, Atsuhiro, Fujii, Yumiko, Maeda, Shin, Koike, Kazuhiko, Hatakeyama, Masanori
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421872/
https://ncbi.nlm.nih.gov/pubmed/25944120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10024
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