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A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
Protein aggregation plays a key role in neurodegenerative disease, giving rise to small oligomers that may become cytotoxic to cells. The fundamental microscopic reactions taking place during aggregation, and their rate constants, have been difficult to determine due to lack of suitable methods to i...
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| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Pub. Group
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4421837/ https://ncbi.nlm.nih.gov/pubmed/25926130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8025 |
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