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Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis
Estrogen-induced cholestasis is characterized by impaired hepatic uptake and biliary bile acids secretion because of changes in hepatocyte transporter expression. The induction of heme oxygenase-1 (HMOX1), the inducible isozyme in heme catabolism, is mediated via the Bach1/Nrf2 pathway, and protects...
में बचाया:
में प्रकाशित: | J Cell Mol Med |
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मुख्य लेखकों: | , , , , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
BlackWell Publishing Ltd
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420596/ https://ncbi.nlm.nih.gov/pubmed/25683492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12401 |
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