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Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells

BACKGROUND: Pancreatic cancer is recognized as one of the most fatal tumors due to its aggressiveness and resistance to therapy. Statins were previously shown to inhibit the proliferation of cancer cells via various signaling pathways. In healthy tissues, statins activate the heme oxygenase pathway,...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Vanova, K., Boukalova, S., Gbelcova, H., Muchova, L., Neuzil, J., Gurlich, R., Ruml, T., Vitek, L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866069/
https://ncbi.nlm.nih.gov/pubmed/27175805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2343-9
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