Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells

BACKGROUND: Statin treatment of hypercholesterolemia is accompanied also with depletion of the mevalonate intermediates, including farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) necessary for proper function of small GTPases. These include Ras proteins, prevalently mutated in p...

詳細記述

保存先:
書誌詳細
出版年:Lipids Health Dis
主要な著者: Gbelcová, Helena, Rimpelová, Silvie, Knejzlík, Zdeněk, Šáchová, Jana, Kolář, Michal, Strnad, Hynek, Repiská, Vanda, D’Acunto, Walter Cosimo, Ruml, Tomáš, Vítek, Libor
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738693/
https://ncbi.nlm.nih.gov/pubmed/29262834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0641-0
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料