The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells

BACKGROUND: Statins (HMG-CoA reductase inhibitors) represent a major class of compounds for the treatment of hypercholesterolemia due to their ability to inhibit de novo cholesterol synthesis. In addition to their hypolipidemic effects, chemoprotective properties have been attributed to statins as w...

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Detalhes bibliográficos
Main Authors: Gbelcová, Helena, Švéda, Martin, Laubertová, Lucia, Varga, Ivan, Vítek, Libor, Kolář, Michal, Strnad, Hynek, Zelenka, Jaroslav, Böhmer, Daniel, Ruml, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765626/
https://ncbi.nlm.nih.gov/pubmed/23961716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-126
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