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Bile acids decrease intracellular bilirubin levels in the cholestatic liver: implications for bile acid-mediated oxidative stress

High plasma concentrations of bile acids (BA) and bilirubin are hallmarks of cholestasis. BA are implicated in the pathogenesis of cholestatic liver damage through mechanisms involving oxidative stress, whereas bilirubin is a strong antioxidant. We evaluated the roles of bilirubin and BA on mediatin...

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Bibliografski detalji
Glavni autori: Muchova, Lucie, Vanova, Katerina, Zelenka, Jaroslav, Lenicek, Martin, Petr, Tomas, Vejrazka, Martin, Sticova, Eva, Vreman, Hendrik Jan, Wong, Ronald James, Vitek, Libor
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822628/
https://ncbi.nlm.nih.gov/pubmed/20518850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01098.x
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