Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model

Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carrying HBV genome and the genetic background of the mou...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pan, Danzhen, Lin, Yong, Wu, Weimin, Song, Jingjiao, Zhang, Ejuan, Wu, Chunchen, Chen, Xinwen, Hu, Kanghong, Yang, Dongliang, Xu, Yang, Lu, Mengji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420481/
https://ncbi.nlm.nih.gov/pubmed/25942393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125658
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