Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model

Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carrying HBV genome and the genetic background of the mou...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Pan, Danzhen, Lin, Yong, Wu, Weimin, Song, Jingjiao, Zhang, Ejuan, Wu, Chunchen, Chen, Xinwen, Hu, Kanghong, Yang, Dongliang, Xu, Yang, Lu, Mengji
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420481/
https://ncbi.nlm.nih.gov/pubmed/25942393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125658
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