Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model

Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carrying HBV genome and the genetic background of the mou...

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Udgivet i:PLoS One
Main Authors: Pan, Danzhen, Lin, Yong, Wu, Weimin, Song, Jingjiao, Zhang, Ejuan, Wu, Chunchen, Chen, Xinwen, Hu, Kanghong, Yang, Dongliang, Xu, Yang, Lu, Mengji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420481/
https://ncbi.nlm.nih.gov/pubmed/25942393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125658
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