Biological interpretation of genome-wide association studies using predicted gene functions

The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systematically prioritize the most likely causal genes at associated loc...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja, Gustafsson, Stefan, Esko, Tonu, Frayling, Tim, Speliotes, Elizabeth K., Boehnke, Michael, Raychaudhuri, Soumya, Fehrmann, Rudolf S.N., Hirschhorn, Joel N., Franke, Lude
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420238/
https://ncbi.nlm.nih.gov/pubmed/25597830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6890
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