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Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

BACKGROUND: The lectin griffithsin (GRFT) is a potent antiviral agent capable of prevention and treatment of infections caused by a number of enveloped viruses and is currently under development as an anti-HIV microbicide. In addition to its broad antiviral activity, GRFT is stable at high temperatu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Retrovirology
Hauptverfasser: Moulaei, Tinoush, Alexandre, Kabamba B, Shenoy, Shilpa R, Meyerson, Joel R, Krumpe, Lauren RH, Constantine, Brian, Wilson, Jennifer, Buckheit, Robert W, McMahon, James B, Subramaniam, Sriram, Wlodawer, Alexander, O’Keefe, Barry R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419512/
https://ncbi.nlm.nih.gov/pubmed/25613831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0127-3
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