Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes

BACKGROUND: Oxygen and glucose metabolism play pivotal roles in many (patho)physiological conditions. In particular, oxygen and glucose deprivation (OGD) during ischemia and stroke results in extensive tissue injury and cell death. RESULTS: Using time-resolved ribosome profiling, we assess gene expr...

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Detaylı Bibliyografya
Yayımlandı:Genome Biol
Asıl Yazarlar: Andreev, Dmitry E, O’Connor, Patrick BF, Zhdanov, Alexander V, Dmitriev, Ruslan I, Shatsky, Ivan N, Papkovsky, Dmitri B, Baranov, Pavel V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419486/
https://ncbi.nlm.nih.gov/pubmed/25943107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0651-z
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