Translation initiation downstream from annotated start codons in human mRNAs coevolves with the Kozak context

Eukaryotic translation initiation involves preinitiation ribosomal complex 5′-to-3′ directional probing of mRNA for codons suitable for starting protein synthesis. The recognition of codons as starts depends on the codon identity and on its immediate nucleotide context known as Kozak context. When t...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Benitez-Cantos, Maria S., Yordanova, Martina M., O'Connor, Patrick B.F., Zhdanov, Alexander V., Kovalchuk, Sergey I., Papkovsky, Dmitri B., Andreev, Dmitry E., Baranov, Pavel V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397870/
https://ncbi.nlm.nih.gov/pubmed/32669370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.257352.119
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