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Translation initiation downstream from annotated start codons in human mRNAs coevolves with the Kozak context

Eukaryotic translation initiation involves preinitiation ribosomal complex 5′-to-3′ directional probing of mRNA for codons suitable for starting protein synthesis. The recognition of codons as starts depends on the codon identity and on its immediate nucleotide context known as Kozak context. When t...

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Bibliografiset tiedot
Julkaisussa:Genome Res
Päätekijät: Benitez-Cantos, Maria S., Yordanova, Martina M., O'Connor, Patrick B.F., Zhdanov, Alexander V., Kovalchuk, Sergey I., Papkovsky, Dmitri B., Andreev, Dmitry E., Baranov, Pavel V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397870/
https://ncbi.nlm.nih.gov/pubmed/32669370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.257352.119
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