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Preferential Selection of the 5′-Terminal Start Codon on Leaderless mRNAs by Mammalian Mitochondrial Ribosomes
Mammalian mitochondrial mRNAs are basically leaderless, having few or no untranslated nucleotides prior to the 5′-start codon. We demonstrate here that mammalian mitochondrial 55 S ribosomes preferentially form initiation complexes at a 5′-terminal AUG codon over an internal AUG. The preferential us...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934702/ https://ncbi.nlm.nih.gov/pubmed/20610392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149054 |
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