Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling

Mitochondrial uncoupling is implicated in many patho(physiological) states. Using confocal live cell imaging and an optical O(2) sensing technique, we show that moderate uncoupling of the mitochondria with plecomacrolide Baf (bafilomycin A1) causes partial depolarization of the mitochondria and deep...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhdanov, Alexander V., Dmitriev, Ruslan I., Papkovsky, Dmitri B.
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2012
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497721/
https://ncbi.nlm.nih.gov/pubmed/22943412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20120085
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires