DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma

BACKGROUND: Alcohol is a well-known risk factor for hepatocellular carcinoma (HCC), but the mechanisms underlying the alcohol-related hepatocarcinogenesis are still poorly understood. Alcohol alters the provision of methyl groups within the hepatic one-carbon metabolism, possibly inducing aberrant D...

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Publicat a:Clin Epigenetics
Autors principals: Udali, Silvia, Guarini, Patrizia, Ruzzenente, Andrea, Ferrarini, Alberto, Guglielmi, Alfredo, Lotto, Valentina, Tononi, Paola, Pattini, Patrizia, Moruzzi, Sara, Campagnaro, Tommaso, Conci, Simone, Olivieri, Oliviero, Corrocher, Roberto, Delledonne, Massimo, Choi, Sang-Woon, Friso, Simonetta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419480/
https://ncbi.nlm.nih.gov/pubmed/25945129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0077-1
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