Hypermethylation of MT1G and MT1H CpGs Promoter Sites and High Serum Levels of Cu Affect Survival Rate of Patients Affected by Hepatocellular Carcinoma

OBJECTIVES: Recent evidences suggest a principal role of trace elements and metallothioneins (MTs), proteins involved in metal ions homeostasis and detoxification, in hepatocellular carcinogenesis. The study was designed to evaluate whether serum and liver tissue concentrations of the trace elements...

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Bibliografiske detaljer
Udgivet i:Curr Dev Nutr
Main Authors: Santis, Domenica De, Udali, Silvia, Ruzzenente, Andrea, Beschin, Greta, Pattini, Patrizia, Franceschi, Antonia, Moruzzi, Sara, Guglielmi, Alfredo, Olivieri, Oliviero, Choi, Sang-Woon, Friso, Simonetta
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Vitamins and Minerals
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259223/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa067_018
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