One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation

Several polymorphic gene variants within one-carbon metabolism, an essential pathway for nucleotide synthesis and methylation reactions, are related to cancer risk. An aberrant DNA methylation is a common feature in cancer but whether the link between one-carbon metabolism variants and cancer occurs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Moruzzi, Sara, Guarini, Patrizia, Udali, Silvia, Ruzzenente, Andrea, Guglielmi, Alfredo, Conci, Simone, Pattini, Patrizia, Martinelli, Nicola, Olivieri, Oliviero, Tammen, Stephanie A., Choi, Sang-Woon, Friso, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624642/
https://ncbi.nlm.nih.gov/pubmed/28968444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185792
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