Hypermethylation of MT1G and MT1H CpGs Promoter Sites and High Serum Levels of Cu Affect Survival Rate of Patients Affected by Hepatocellular Carcinoma

OBJECTIVES: Recent evidences suggest a principal role of trace elements and metallothioneins (MTs), proteins involved in metal ions homeostasis and detoxification, in hepatocellular carcinogenesis. The study was designed to evaluate whether serum and liver tissue concentrations of the trace elements...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Curr Dev Nutr
Autori principali: Santis, Domenica De, Udali, Silvia, Ruzzenente, Andrea, Beschin, Greta, Pattini, Patrizia, Franceschi, Antonia, Moruzzi, Sara, Guglielmi, Alfredo, Olivieri, Oliviero, Choi, Sang-Woon, Friso, Simonetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Vitamins and Minerals
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259223/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa067_018
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