Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase

Urea cycle defects and acute or chronic liver failure are linked to systemic hyperammonemia and often result in cerebral dysfunction and encephalopathy. Although an important role of the liver in ammonia metabolism is widely accepted, the role of ammonia metabolizing pathways in the liver for mainte...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Qvartskhava, Natalia, Lang, Philipp A., Görg, Boris, Pozdeev, Vitaly I., Ortiz, Marina Pascual, Lang, Karl S., Bidmon, Hans J., Lang, Elisabeth, Leibrock, Christina B., Herebian, Diran, Bode, Johannes G., Lang, Florian, Häussinger, Dieter
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418919/
https://ncbi.nlm.nih.gov/pubmed/25870278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423968112
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