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Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase
Urea cycle defects and acute or chronic liver failure are linked to systemic hyperammonemia and often result in cerebral dysfunction and encephalopathy. Although an important role of the liver in ammonia metabolism is widely accepted, the role of ammonia metabolizing pathways in the liver for mainte...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418919/ https://ncbi.nlm.nih.gov/pubmed/25870278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423968112 |
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