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Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase

Urea cycle defects and acute or chronic liver failure are linked to systemic hyperammonemia and often result in cerebral dysfunction and encephalopathy. Although an important role of the liver in ammonia metabolism is widely accepted, the role of ammonia metabolizing pathways in the liver for mainte...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qvartskhava, Natalia, Lang, Philipp A., Görg, Boris, Pozdeev, Vitaly I., Ortiz, Marina Pascual, Lang, Karl S., Bidmon, Hans J., Lang, Elisabeth, Leibrock, Christina B., Herebian, Diran, Bode, Johannes G., Lang, Florian, Häussinger, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418919/
https://ncbi.nlm.nih.gov/pubmed/25870278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423968112
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