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Mechanism of DNA Depurination by Carcinogens in Relation to Cancer Initiation
Depurinating DNA adducts formed by aromatic hydrocarbons and catechol estrogen quinones play a major role in cancer initiation. Most of these adducts depurinate instantaneously, but some guanine adducts depurinate from DNA with half-lives of hours. We report here, that after 10 h at 37 °C, reaction...
Guardat en:
| Publicat a: | IUBMB Life |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418633/ https://ncbi.nlm.nih.gov/pubmed/22162200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.586 |
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