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Depurinating estrogen–DNA adducts in the etiology and prevention of breast and other human cancers
Experiments on estrogen metabolism, formation of DNA adducts, mutagenicity, cell transformation and carcinogenicity have led to and supported the hypothesis that the reaction of specific estrogen metabolites, mostly the electrophilic catechol estrogen-3,4-quinones, with DNA can generate the critical...
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| Publicado no: | Future Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422115/ https://ncbi.nlm.nih.gov/pubmed/20021210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.137 |
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