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Depurinating estrogen–DNA adducts in the etiology and prevention of breast and other human cancers

Experiments on estrogen metabolism, formation of DNA adducts, mutagenicity, cell transformation and carcinogenicity have led to and supported the hypothesis that the reaction of specific estrogen metabolites, mostly the electrophilic catechol estrogen-3,4-quinones, with DNA can generate the critical...

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Detaylı Bibliyografya
Yayımlandı:Future Oncol
Asıl Yazarlar: Cavalieri, Ercole L, Rogan, Eleanor G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422115/
https://ncbi.nlm.nih.gov/pubmed/20021210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.137
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